| 摘要 |
A method for the synthesis of semiconductor nanoparticles within a protein template, wherein the semiconductor is selected from CdSe, CdTe, ZnSe, ZnS and ZnTe, the method comprising forming a reaction mixture by combining in a liquid medium a cation source selected from cadmium or zinc ions and an anion source selected from sulfur, selenium or tellurium ions in the presence of a source of protein which is capable of acting as a template for the formation of nanoparticles and maintaining the liquid medium at a temperature of at least 24{C for a time sufficient to permit nanoparticle formation within the protein template, with the proviso that when the cation source is cadmium, the anion source is not sulfur. The protein template may comprise flagellar L-P rings, microtubules, bacteriophages, chaperonins, virus capsids or preferably members of the ferritin family, most preferably apoferritin. The encapsulated nanoparticle may be subjected to membrane filtration. Also independently claimed is a composition of protein-encapsulated semiconductor nanoparticles wherein the semiconductor is selected from CdSe, CdTe, ZnSe, ZnS or ZnTe. |
