Method for producing seven-membered diether compounds and intermediates thereof

摘要

3,4-Dihydro(2H)-1,5-benzodioxepin-3-one and its intermediates is produced by reacting catechols with 1,3-dihaloacetones in the presence of sodium carbonate through the removal of hydrogen halide. Production of 3,4-dihydro(2H)-1,5-benzodioxepin-3-one and its intermediates, of formula (3) comprises reacting catechols of formula (5) with 1,3-dihaloacetones of formula (6) in the presence of sodium carbonate through the removal of hydrogen halide. [Image] R1>-R4>H, alkyl, or alkenyl;and X : halogen. It is provided that R1>-R4> as a whole do not comprise more than 10 carbon atoms (C), and they may be combined together to form a carbon ring when the two adjacent groups comprise alkyl or alkenyl group.