| 发明名称 |
A PROCESS FOR THE PREPARATION OF agr; CHLOROKETONES. |
| 摘要 |
<p>The present invention relates to a process for the preparation of agr; chloroketones, such as 4-phenyl-3-t-butyloxy-carbonylamino)-2-keto-1-chlorobutane by reacting certain aryl amino acid esters, e.g. N-(2-t-butoxycarbonyl)-L-phenylalanine-4-nitrophenyl ester, with a sulfur ylide compound to form the corresponding keto ylide compound which is then treated with a source of chloride and an organic acid.</p> |
| 申请公布号 |
MXPA03001314(A) |
申请公布日期 |
2004.04.05 |
| 申请号 |
MX2003PA01314 |
申请日期 |
2001.07.20 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
SCHWINDEN, MARK, D. |
| 分类号 |
C07D303/46;C07C221/00;C07C269/06;C07C271/16;C07C271/18;C07C315/04;C07C317/28;C07D303/36;(IPC1-7):C07C45/61;C07D301/00;C07D301/24 |
主分类号 |
C07D303/46 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
