摘要 |
<P>PROBLEM TO BE SOLVED: To directly clone a new DNA containing a region which encodes a protein from a cDNA genomic library derived from human adult's whole brain and human embryo's whole brain, to determine a base sequence of the same, and identify a function of the same. <P>SOLUTION: This DNA contains a base sequence which encodes a polypeptide (a) or a polypeptide (b), wherein the polypeptide (a) is composed of an amino acid sequence identical or substantially identical to an amino acid sequence expressed by a specific sequence, and the polypeptide (b) is composed of another amino acid sequence in which a part of amino acids are deleted from, substituted in, or added to the amino acid sequence expressed by the specific sequence, and has biological activity substantially homologous to function of the polypeptide (a). A genetic architectural substance contains the DNA. A recombinant polypeptide is encoded by the genetic architectural substance. An antibody acts against the polypeptide or the recombinant polypeptide. <P>COPYRIGHT: (C)2004,JPO |