发明名称 Antibodies to human IL-1beta.
摘要 An IL-1&bgr; binding molecule, in particular an antibody to human IL-1&bgr;, especially a human antibody to human IL-1&bgr; is provided, wherein the CDRs of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-1 mediated disease or disorder, e.g. osteoarthritis, osteoporosis and other inflammatory arthritides.
申请公布号 ZA200301275(B) 申请公布日期 2004.04.02
申请号 ZA20030001275 申请日期 2003.02.17
申请人 NOVARTIS AG. 发明人 HERMANN GRAM;DI PADOVA, FRANCO, E.
分类号 C12N15/09;A61K39/395;A61P1/04;A61P3/10;A61P11/00;A61P13/12;A61P19/02;A61P19/04;A61P25/00;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P37/08;C07K16/24;C07K19/00;C12P21/02 主分类号 C12N15/09
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