发明名称 PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC AMINO-SUBSTITUTED COMPOUND
摘要 PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a bicyclic amino-substituted compound, capable of inhibiting production of an inflammatory cytokine. SOLUTION: This pharmaceutical composition contains a compound having general formula (I) (A is a trivalent group, such as pyrimidine and pyrrol, which may be substituted; R<SP>1</SP>is an aryl or an heteroaryl of which the each may be substituted; R<SP>2</SP>is a heteroaryl which may be substituted; and R<SP>3</SP>is indolizine or the like), a pharmacologically acceptable salt thereof, an ester thereof or the other derivative thereof as an active ingredient. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004099600(A) 申请公布日期 2004.04.02
申请号 JP20030199729 申请日期 2003.07.22
申请人 SANKYO CO LTD 发明人 KIMURA TOMIO;OKAWA NOBUYUKI;AOKI KAZUMA;NAKAO AKIRA;NAGASAKI TAKAMI;YAMAZAKI TAKANORI
分类号 C07D491/20;A61K31/444;A61P1/04;A61P1/16;A61P3/10;A61P9/10;A61P11/06;A61P13/12;A61P17/06;A61P19/02;A61P19/10;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D471/04;(IPC1-7):A61K31/444 主分类号 C07D491/20
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