摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a bicyclic amino-substituted compound, capable of inhibiting production of an inflammatory cytokine. SOLUTION: This pharmaceutical composition contains a compound having general formula (I) (A is a trivalent group, such as pyrimidine and pyrrol, which may be substituted; R<SP>1</SP>is an aryl or an heteroaryl of which the each may be substituted; R<SP>2</SP>is a heteroaryl which may be substituted; and R<SP>3</SP>is indolizine or the like), a pharmacologically acceptable salt thereof, an ester thereof or the other derivative thereof as an active ingredient. COPYRIGHT: (C)2004,JPO
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