发明名称 DERIVES 1,4 DE PIPERAZINE SUBSTITUES UTILISES COMME BLOQUEURS A1-ADRENOCEPTEUR URO-SELECTIFS.
摘要 <p>The present invention relates to a novel 1,4-disubstituted piperazine derivatives of Formula I, and their pharmaceutically acceptable acid addition salts having excellent uro-selective alpha<SUB>1</SUB>-adrenoceptor antagonistic activity exceeding those of previously described compounds. The compounds of the present invention hold promise for treating the symptoms of benign prostatic hyperplasia (BPH). The invention also relates to methods for making the novel compounds, pharmaceutical compositions containing the compounds, and method of treating the symptoms of benign prostatic hyperplasia using the compounds.</p>
申请公布号 MA26064(A1) 申请公布日期 2004.04.01
申请号 MA20030027188 申请日期 2003.05.30
申请人 RANBAXY LABORATORIES LIMITED 发明人 NITYA ANAND;SANJAY JAIN;NEELIMA SINHA;ANITA CHUNG;JANG BAHADUR GUPTA
分类号 A61K31/497;A61P13/08;A61P43/00;C07D209/48;(IPC1-7):C07D209/48;A61K31/40 主分类号 A61K31/497
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