OCTAHYDRO-2-H-NAPHTHO[1,2-F] INDOLE-4-CARBOXAMIDE DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
摘要
The present invention encompasses compounds of Formula I: or pharmaceuticall y acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.
申请公布号
CA2499150(A1)
申请公布日期
2004.04.01
申请号
CA20032499150
申请日期
2003.09.17
申请人
MERCK & CO., INC.
发明人
TAYLOR, GAYLE E.;TATA, JAMES R.;SINCLAIR, PETER J.;GOULET, JOUNG L.;HUNT, JULIANNE A.;BALKOVEC, JAMES M.;GRAHAM, DONALD W.;ASTER, SUSAN D.;KALLASHI, FLORIDA;ALI, AMJAD