发明名称 Compounds useful as reversible inhibitors of cysteine proteases
摘要 Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (Ia) and (Ib) where R1, R2, R3, R4, R5, R6, R8, R9 and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.
申请公布号 US2004063679(A1) 申请公布日期 2004.04.01
申请号 US20020256512 申请日期 2002.09.27
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS INC. 发明人 BEKKALI YOUNES;SPERO DENICE MARY;SUN SANXING;THOMSON DAVID S.;WARD YANCEY D.;YOUNG ERICK R.R.;HICKEY EUGENE R.;LIU WEIMIN;PATEL USHA R.
分类号 C07D295/12;A61K31/277;A61K31/341;A61K31/351;A61K31/428;A61K31/517;A61K31/536;A61K31/5375;A61K31/5377;A61P1/04;A61P3/10;A61P5/14;A61P9/10;A61P11/06;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P21/04;A61P25/00;A61P25/28;A61P29/00;A61P37/00;A61P37/02;A61P37/06;A61P43/00;C07C257/20;C07C269/06;C07C271/20;C07C271/64;C07C319/20;C07C323/41;C07C323/60;C07D211/22;C07D213/30;C07D213/57;C07D239/80;C07D263/32;C07D265/24;C07D275/06;C07D277/30;C07D295/14;C07D295/215;C07D307/12;C07D307/54;C07D309/08;C07D309/12;C07D333/24;C07D401/04;C07D401/06;(IPC1-7):A61K31/55;A61K31/541;A61K31/537;A61K31/496;A61K31/497;C07D417/02;C07D413/02;C0743/02 主分类号 C07D295/12
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