IMIDAZOPYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS

摘要

This invention provides a compound of the formula (I): (I) 5 wherein Rl represents a hydrogen atom or a halogen atom; R2 represents a methyl group o r an ethyl group; R3 represents a branched alkyl group having from 3 to 6 carb on atoms or an alkyl group having from 3 to 6 carbon atoms substituted by an alkoxy group having from 1 to 6 carbon atoms; with the proviso that when the terminal carbon atom of said alkyl group is substituted by said alkoxy gorou p, said alkyl group is a branched alkyl group; and pharmaceutically acceptable salts thereof. These compounds have 5-HT4 receptor binding activity, and thu s are usefulfor the treatment of gastroesophageal reflux disease, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome or the like in mammalian, especially humans. This invention also provides a pharmaceutical composition comprising the above compound.