发明名称 |
PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) |
摘要 |
The present invention relates to compounds of formula I which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia , Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases. Or pharmaceutically acceptable salts or prodrugs thereof, wherein X,R,R1,R2 and R3 have the definitions given in the description.
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申请公布号 |
CA2497725(A1) |
申请公布日期 |
2004.04.01 |
申请号 |
CA20032497725 |
申请日期 |
2003.09.15 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
MADAR, DAVID;KOPECKA, HANA;LI, XIAOFENG;FEENSTRA, MELISSA J.;SZCZEPANKIEWICZ, BRUCE G.;STEWART, KENT D.;PEI, ZHONGHUA;YONG, HONG;WIEDEMAN, PAUL E.;DJURIC, STEVAN W.;PIREH, DAISY;LONGENECKER, KENTON;SHAM, HING L. |
分类号 |
A61P37/02;C07D207/16;C07D207/26;C07D207/27;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D417/12;(IPC1-7):C07D207/16;A61K31/401;A61K31/443;A61K31/506 |
主分类号 |
A61P37/02 |
代理机构 |
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代理人 |
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地址 |
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