ANTISENSE MODULATION OF HMG-COA REDUCTASE EXPRESSION
摘要
Antisense compounds, compositions and methods are provided for modulating the expression of HMG-CoA reductase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding HMG-CoA reductase. Methods of using these compounds for modulation of HMG-CoA reductase expression and for treatment of diseases associated with expression of HMG-CoA reductase are provided.
申请公布号
WO2004005460(A3)
申请公布日期
2004.04.01
申请号
WO2003US16249
申请日期
2003.07.02
申请人
ISIS PHARMACEUTICALS INC.;DEAN, NICHOLAS, M.;FREIER, SUSAN, M.;DOBIE, KENNETH, W.
发明人
DEAN, NICHOLAS, M.;FREIER, SUSAN, M.;DOBIE, KENNETH, W.