发明名称 |
MODULATION OF ENDOTHELIAL CELL SURFACE RECEPTOR ACTIVITY IN THE REGULATION OF ANGIOGENESIS |
摘要 |
A method of modulating angiogenesis in a vertebrate subject, the method comprising administering to the vertebrate subject an ECRTP/DEP-1 receptor activity-modulating amount of a composition, whereby an ECRTP/DEP-1 receptor within the vertebrate subject is contacted by the composition; and modulating angiogenesis through the contacting of the ECRTP/DEP-1 receptor with the composition. Optionally, the composition includes a monoclonal antibody which preferentially binds the ECRTP/DEP-1 receptor. |
申请公布号 |
EP1109578(A4) |
申请公布日期 |
2004.03.31 |
申请号 |
EP19990945368 |
申请日期 |
1999.08.31 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
DANIEL, THOMAS, O.;TAKAHASHI, TAKAMUNE |
分类号 |
G01N33/577;A61K39/395;A61K45/00;A61K47/48;A61P9/14;A61P35/00;A61P35/04;C07K16/28;C07K16/40;C12N5/10;C12N15/02;C12P21/08;C12R1/91 |
主分类号 |
G01N33/577 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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