| 发明名称 |
Nucleozymes |
| 摘要 |
Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts. Also described are methods for preparing the nucleozymes along with methods of using nucleozymes, e.g., as therapeutic agents.
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| 申请公布号 |
US6713456(B1) |
申请公布日期 |
2004.03.30 |
| 申请号 |
US19950459340 |
申请日期 |
1995.06.02 |
| 申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;UNIVERSITY OF MONTREAL |
发明人 |
USMAN NASSIM;CEDERGREN ROBERT J.;PERREAULT JEAN-PIERRE;YANG JING-HUA;RICH ALEXANDER |
| 分类号 |
C12N9/00;A61K31/70;A61K38/00;A61K48/00;A61P31/18;C07H21/04;C12N15/113;(IPC1-7):A61K48/00;C12Q1/68;C12P19/34 |
主分类号 |
C12N9/00 |
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