| 摘要 |
The present invention provides for a method for inhibiting growth of a bacterium which consists essentially of contacting the bacterium with a compound having the structure:wherein each of R1, R2, R3, R4, R5 and R6 may be independently H, F, Cl, Br, I, -OH, -OR7, -CN, -COR7, -SR7, -N(R7)2, -NR7COR8, -NO2, -(CH2)pOR7, -(CH2)pX(R7)2, -(CH2)pXR7COR8, a straight chain or branched, substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, C3-C10 cycloalkyl, C3-C10 cycloalkenyl, thioalkyl, methylene thioalkyl, acyl, phenyl, substituted phenyl, or heteroaryl; wherein a linkage to the benzene ring may alternatively be -N-, -S--, -O- or -C-; wherein R7 or R8 may be independently H, F, Cl, Br, I, -OH, -CN, -COH, -SH2, -NH2, -NHCOH, -(CH2)pOH, -(CH2)pX(CH2), -(CH2)pXCOH, a straight chain or branched, substituted or unsubstituted C1-C10 alkyl, thioalkyl, methylene thioalkyl, acyl, phenyl, substituted phenyl, or heteroaryl; wherein A may be -N2-, -NH-, -C=C=CH2-, -C=C-C2HOH-, -C=C-CH2-, -CH2-CH2-O-, -CH2-CH2-CH2-O-, -S-, -S(=O)2, -C=O-, -C=O-O-, -NH-C=O-, -C=O-NH-.
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