发明名称 |
LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES |
摘要 |
Linear substituted oligoalkyleneimine molecules and libraries of molecules a re disclosed, as an their methods of synthesis and use in acceptor binding assays. Each molecule or chain of a library contains the sa me number of 2 to about 10 substituted alkyleneimine repeating units whose substituents are reduced amino acid side chains bonded to the repeating units at a position alpha to the nitrogen atom, and the member chains of a library are present in equimolar amounts. The chains of a library contain one or more predetermined reduced amino acid side chain-substituted repeating units at one or more predetemvned positions of the substituted oligoalkyleneimine chain. The library contains equimolar amounts of at least six different reduced amino acid side chain-substituted repeating units at one or more of the same predetermined positions of the substituted oligoalkyleneimine chain. Particularly preferred linear substituted oligoalkyleneimine molecules and libraries are linear substituted oligoethyleneimines.
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申请公布号 |
CA2163240(C) |
申请公布日期 |
2004.03.30 |
申请号 |
CA19942163240 |
申请日期 |
1994.05.13 |
申请人 |
HOUGHTEN PHARMACEUTICALS, INC. |
发明人 |
HOUGHTEN, RICHARD A.;CUERVO, JULIO HERNAN;WEITL, FRED F. |
分类号 |
B01J19/00;C07K1/04;C40B40/10;(IPC1-7):C07K17/00;G01N33/543;G01N33/68 |
主分类号 |
B01J19/00 |
代理机构 |
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主权项 |
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