| 发明名称 |
ORTHOPOXVIRUS VECTORS, GENES AND PRODUCTS THEREOF |
| 摘要 |
<p>An orthopoxvirus vector, such as vaccinia, is described in which the A52R protein from vaccinia, or a closely related protein from any orthopoxvirus is not expressed or is expressed but is non-functional. Also described is the use of a vaccinia virus A52R protein or a closely related protein from any orthopoxvirus, or a functional peptide, peptidometic, fragment or derivative thereof, or a DNA vector expressing any of the above in the modulation and/or inhibition of IL1R/TLR superfamily signalling.</p> |
| 申请公布号 |
AU2003264836(A1) |
申请公布日期 |
2004.03.29 |
| 申请号 |
AU20030264836 |
申请日期 |
2003.09.05 |
| 申请人 |
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN |
发明人 |
GERALDINE MALONEY;LUKE, ANTHONY, JOHN O'NEILL;ANDREW, GRAHAM BOWIE;MARY, THERESA HARTE;GEOFFREY, LILLEY SMITH;ISMAR, ROCHA HAGA |
| 分类号 |
A61K35/76;A61K38/00;A61K38/11;A61K38/16;A61K39/00;A61K39/12;A61K39/285;C07K14/07;C12N7/00;C12N7/04;C12N15/86;C12N15/863;(IPC1-7):C12N15/86 |
主分类号 |
A61K35/76 |
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