| 摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to tricyclic Delta3- piperidines of the general formula (I) Delta3- wherein X means oxygen or sulfur atom; means hydrogen atom, halogen atom, R1-alkyl or C1-6-alkyloxy-group; Alk means C1-4-alkanediyl; D is given in the invention claim. Invention describes also methods for preparing compounds of the formula (I) and a pharmaceutical composition eliciting an antagonistic activity with respect to the central C1-6-adrenoreceptor based on these compounds. Invention provides preparing new compounds exhibiting valuable biological properties. EFFECT: improved preparing methods, valuable medicinal properties of compounds. 11 cl, 17 dwg, 5 tbl, 4 ex |
