发明名称 ПРИМЕНЕНИЕ CD25-СВЯЗЫВАЮЩИХ МОЛЕКУЛ ДЛЯ ЛЕЧЕНИЯ ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА
摘要 Use of a CD25 binding molecule which comprises at least one antigen binding site comprising at least one domain which comprises in sequence, the hypervariable regions CDR1, CDR2 and CDR3; said CDR1 having the amino acid sequence Arg-Tyr-Trp-Met-His, said CDR2 having the amino acid sequence Ala-Ile-Tyr-Pro-Gly-Asn-Ser-Asp-Thr-Ser-Tyr-Asn-Gln-Lys-Phe-Glu-Gly, and said CDR3 having the amino acid sequence Asp-Tyr-Gly-Tyr-Tyr-Phe-Asp-Phe, in the treatment of inflammatory disease of the gastro-intestinal tract.
申请公布号 RU2002127800(A) 申请公布日期 2004.03.27
申请号 RU20020127800 申请日期 2001.03.28
申请人 НОВАРТИС АГ (CH) 发明人 АДАМ Хансйёрг (DE);ФЭРБЕР Лотар (DE)
分类号 A61K39/395;A61P1/04;A61P29/00;A61P37/00;C07K16/28 主分类号 A61K39/395
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