| 摘要 |
An antigenic composition comprising a selected antigen from a pathogenic virus, bacterium, fungus, parasite, a cancer cell or tumor cell, an allergen, or from an amyloid peptide protein. The antigen is combined with: (1) 3-0-deacylated monophosphoryl lipid A or monophosphoryl lipid A. (2) a cytokine or lymphokine selected from the group consisting of granulocyte macrophage colony stimulating factor and interleukin 12. Specifically the antigen may be selected from the Human Immunodeficiency Virus (HIV), Simian Immunodeficiency Virus (SIV), Neisseria gonorrhoeae and human Respiratory Syncytial Virus (RSV). The use of the antigenic composition as described above to increase the ability to elicit an immune response in a vertebrate host. |
