| 发明名称 |
HYDROXAMIC ACID DERIVATIVES |
| 摘要 |
Novel hydroxamic acid derivatives, e.g., of formula (I), wherein R1, R2, R3 and R4 are as defined, are found to be useful as pharmaceuticals, e.g., for the suppression of TNF release and the treatment of autoimmune and inflammatory diseases, e.g., multiple sclerosis and rheumatoid arthritis. Methods of making the compounds, novel intermediates, and pharmaceutical compositions comprising the compounds are provided. |
| 申请公布号 |
WO03084941(A3) |
申请公布日期 |
2004.03.25 |
| 申请号 |
WO2003EP03644 |
申请日期 |
2003.04.08 |
| 申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;JANSER, PHILIPP;MILTZ, WOLFGANG;NEUMANN, ULF |
发明人 |
JANSER, PHILIPP;MILTZ, WOLFGANG;NEUMANN, ULF |
| 分类号 |
C07D295/18;A61K31/401;A61K31/445;A61K31/4453;A61K31/495;A61K31/5375;A61P1/02;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P7/06;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P21/04;A61P25/00;A61P25/04;A61P25/06;A61P25/28;A61P27/02;A61P29/00;A61P31/00;A61P31/04;A61P31/18;A61P35/00;A61P35/04;A61P37/00;A61P37/06;A61P41/00;A61P43/00;C07D207/16;C07D211/60;C07D241/04;C07D295/185;C07D295/205 |
主分类号 |
C07D295/18 |
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