A NEW PROCESS FOR THE PREPARATION OF EPOTHILONE DERIVATIVES,NEW EPOTHILONE DERIVATIVES AS WELL AS NEW INTERMEDIATE PRODUCTS FOR THE PROCESS AND THE METHODS OF PREPARING SAME

摘要

The present invention provides a synthesis for the preparation of epothilone derivatives of formula (9) wherein R1 is methyl, and R2 has the meaning of a n unsubstituted or substituted aryl, an unsubstituted or substituted heteroary l or an unsubstituted or substituted heterocyclic radical fused to a benzene nucleus, and salts thereof, and intermediates for the synthesis of a compoun d of formula (9).