| 发明名称 |
SUBSTITUTED AMINOETHERS FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
| 摘要 |
The invention provides compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptid e formation.
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| 申请公布号 |
CA2498269(A1) |
申请公布日期 |
2004.03.25 |
| 申请号 |
CA20032498269 |
申请日期 |
2003.09.10 |
| 申请人 |
PHARMACIA & UPJOHN COMPANY LLC |
发明人 |
BECK, JAMES P.;DROWNS, MATTHEW;WARPEHOSKI, MARTHA A. |
| 分类号 |
A61K31/166;A61K31/277;A61K31/421;A61K31/426;A61K31/4409;A61K31/4439;A61K31/505;A61K31/506;A61P25/28;A61P43/00;C07C231/12;C07C233/78;C07C237/34;C07C253/30;C07C255/57;C07D213/30;C07D213/81;C07D239/26;C07D263/32;C07D277/20;C07D277/30;C07D413/04;C07D413/12;(IPC1-7):C07C233/78;A61K31/443 |
主分类号 |
A61K31/166 |
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