A crystal structure of PIM-1 is described that was determined by X-ray crystallography. The use of PIM-1 crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate PIM- 1 and other PIM kinases.
申请公布号
WO2004024895(A2)
申请公布日期
2004.03.25
申请号
WO2003US29415
申请日期
2003.09.16
申请人
PLEXXIKON, INC.;BREMER, RYAN;IBRAHIM, PRABHA;KUMAR, ABHINAV;MANDIYAN, VALSAN;MILBURN, MICHAEL, V.
发明人
BREMER, RYAN;IBRAHIM, PRABHA;KUMAR, ABHINAV;MANDIYAN, VALSAN;MILBURN, MICHAEL, V.
