| 发明名称 |
RADIOSENSITIZATION USING TEXAPHYRIN |
| 摘要 |
PROBLEM TO BE SOLVED: To obtain texaphyrin for radiosensitization. SOLUTION: A medicinal composition used for a radiosensitizer is prepared by using the texaphyrin. The texaphyrin is an aromatic 5 position (and heptacyclic) macrocycle (enlarged porphyrin) and, may be due to its inherent lipophilic property, shows larger biolocalization in non-neoplasm organs and non-atheroma plaque in neoplasm organ and atheroma each possible to be a malignant or benign tumor. The texaphyrin improves radiation damage and overcomes many defects of conventional radiosensitizers. COPYRIGHT: (C)2004,JPO
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| 申请公布号 |
JP2004091495(A) |
申请公布日期 |
2004.03.25 |
| 申请号 |
JP20030377620 |
申请日期 |
2003.11.06 |
| 申请人 |
UNIV TEXAS SYST;PHARMACYCLICS INC |
发明人 |
SESSLER JONATHAN L;HARRIMAN ANTHONY M;MILLER RICHARD A;MODY TARAK D;HEMMI GREGORY W;KRAAL VLADIMIR A;MAGDA DARREN |
| 分类号 |
A61K31/40;A61K31/407;A61K41/00;A61K47/48;A61K49/00;A61K49/06;A61K49/08;A61K51/00;A61K51/04;A61L2/00;A61P35/02;A61P43/00;B01J31/06;B01J31/16;B01J31/18;C07D487/22;C07H21/00;(IPC1-7):A61K31/407 |
主分类号 |
A61K31/40 |
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