| 摘要 |
A DNA sequence isolated from a soil sample confers early sporulation and increased secondary metabolite production on transformed Actinomycetes, particularly Streptomyces species. Streptomyces strains transformed with this sequence are also provided for use in producing or over-expressing secondary metabolites, particularly antibiotics. A method of overexpressing a secondary metabolite in an Actinomycete is also disclosed. |
