发明名称 TREATMENT OF CNS DISORDERS WITH TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE AND ITS FORMAMIDE
摘要 Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4 - tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3, 4- tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4- dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-~4-(3,4- dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl~formamide, which are also useful.
申请公布号 CA2498152(A1) 申请公布日期 2004.03.25
申请号 CA20032498152 申请日期 2003.09.16
申请人 SEPRACOR INC. 发明人 FANG, QUN KEVIN;CURRIE, MARK;JERUSSI, THOMAS P.
分类号 A61K9/20;A61K9/48;A61K31/135;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;C07C209/62;C07C211/42;(IPC1-7):C07C211/42 主分类号 A61K9/20
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