发明名称 Use of lipopeptides in immunotherapy of HIV+ individuals
摘要 The present invention provides a method for controlling viral rebound in HIV+ individuals after termination of anti-retroviral therapy, the method comprising administering to an HIV+ individual who has undergone anti-retroviral therapy that has been terminated and which HIV+ individual has a viral load of less than or equal to 10,000 copies per ml of plasma and a CD4+ level greater than or equal to 300 cells per mm<3>, at least one lipopeptide comprising a peptide chain of 7 to 100 amino acids which comprises at least one CTL epitope of an HIV protein and which is linked by covalent attachment, optionally via a linker moiety, to a lipid chain comprising from 8 to 20 carbon atoms.
申请公布号 US2004058861(A1) 申请公布日期 2004.03.25
申请号 US20010948965 申请日期 2001.09.07
申请人 CAUDRELIER PIERRE;EL HABIB RAPHAELLE;KLEIN MICHEL 发明人 CAUDRELIER PIERRE;EL HABIB RAPHAELLE;KLEIN MICHEL
分类号 C07K14/16;(IPC1-7):A61K38/16 主分类号 C07K14/16
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