| 发明名称 |
EVALUATION METHOD FOR ESTIMATING PHARMACOKINETICS OF PM USING HEPATOCYTE OF PM OF CYTOCHROME P450 DRUG-METABOLIZING ENZYME HAVING GENETIC POLYMORPHISM |
| 摘要 |
PROBLEM TO BE SOLVED: To estimate the pharmacokinetics of PM (poor metabolizer) by using a hepatocyte of PM of a cytochrome P450 drug-metabolizing enzyme having genetic polymorphism. SOLUTION: In estimating the pharmacokinetics (metabolism) of PM, the hepatocyte of PM of CYP2D6 is used among cytochrome P450 drug-metabolizing enzymes known to have genetic polymorphism. COPYRIGHT: (C)2004,JPO
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| 申请公布号 |
JP2004089085(A) |
申请公布日期 |
2004.03.25 |
| 申请号 |
JP20020255626 |
申请日期 |
2002.08.30 |
| 申请人 |
PFIZER JAPAN INC |
发明人 |
SHIMADA KAORU;TAKASHIMA TADAYUKI |
| 分类号 |
C12Q1/02;C12Q1/26;(IPC1-7):C12Q1/26 |
主分类号 |
C12Q1/02 |
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