| 发明名称 |
IMIDAZO`1,2-A!PYRIDINES |
| 摘要 |
The invention relates to novel imidazopyridine derivatives which are inhibitors of the transforming growth factor, ("TGF")-ß signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-beta type I or activin-like kinase ("ALK")-5 receptor, methods for their preparation and their use in medicine, specifically in the treatment and prevention of a disease state mediated by this pathway. |
| 申请公布号 |
WO2004013138(A3) |
申请公布日期 |
2004.03.25 |
| 申请号 |
WO2003EP08390 |
申请日期 |
2003.07.29 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION;DODIC, NERINA;GELLIBERT, FRANCOISE, JEANNE |
发明人 |
DODIC, NERINA;GELLIBERT, FRANCOISE, JEANNE |
| 分类号 |
A61K31/444;A61K31/496;A61K31/5377;A61P1/04;A61P1/16;A61P9/04;A61P9/08;A61P9/10;A61P11/00;A61P13/12;A61P15/00;A61P17/02;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P25/32;A61P27/02;A61P31/12;A61P41/00;A61P43/00;C07D471/04 |
主分类号 |
A61K31/444 |
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