| 摘要 |
Methods are provided for treating disorders associated with mGlu receptors b y simultaneously inhibiting at least two mGIuRs belonging to at least two different groups. In one embodiment, there are provided methods for treating a disorder associated with mGlu receptors 2, 3, and 5, including administering to a subject in need thereof an effective amount of at least one antagonist which modulates mGIuR2, mGIuR3, and mGIuRS. The disorders treated by the method include, for example, nicotine addiction, cocaine addiction, and depression.
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