发明名称 |
INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE |
摘要 |
This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the preparation of the compounds, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.
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申请公布号 |
CA2497003(A1) |
申请公布日期 |
2004.03.25 |
申请号 |
CA20032497003 |
申请日期 |
2003.09.02 |
申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
KOHRT, JEFFREY THOMAS;LA, FRANCES THU;LEONARD, DANIELE MARIE;FILIPSKI, KEVIN JAMES;BOLTON, GARY LOUIS |
分类号 |
A61K31/17;A61K31/351;A61K31/382;A61K31/40;A61K31/44;A61K31/4458;A61P3/10;A61P7/02;A61P9/00;A61P35/00;C07C311/46;C07C317/32;C07C317/40;C07D207/16;C07D211/76;C07D213/75;C07D309/08;C07D309/14;C07D335/02;(IPC1-7):C07C317/32;A61K31/18 |
主分类号 |
A61K31/17 |
代理机构 |
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代理人 |
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地址 |
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