A transgenic animal with alterations in the H2-Ma gene is prepared by introduction of an altered H2-Ma gene into a host animal. The resulting transgenic animals do not produce functional H2-M molecules.
申请公布号
EP0900002(B1)
申请公布日期
2004.03.24
申请号
EP19970902914
申请日期
1997.01.10
申请人
ORTHO-MCNEIL PHARMACEUTICAL, INC.
发明人
LEUNG, WAI-PING;KARLSSON, LARS;ZHOU, LUBING;PETERSON, PER, A.