| 发明名称 |
HASylated polypeptides, especially HASylated erythropoietin |
| 摘要 |
<p>The present invention relates to hydroxyalkylstarch (HAS)-polypeptide-conjugate (HAS-polypeptide) comprising one or more HAS moecules, wherein each HAS is conjugated to the polypeptide via a carbohydrate moiety or a thioether as well as to methods for the production thereof. In a preferred embodiment, the polypeptide is erythropoietin (EPO).</p> |
| 申请公布号 |
EP1400533(A1) |
申请公布日期 |
2004.03.24 |
| 申请号 |
EP20020020425 |
申请日期 |
2002.09.11 |
| 申请人 |
FRESENIUS KABI DEUTSCHLAND GMBH |
发明人 |
CONRADT, HARALD S.;GRABENHORST, ECKART;NIMTZ, MANFRED;ZANDER, NORBERT;FRANK, RONALD;EICHNER, WOLFRAM |
| 分类号 |
A61K8/73;A61K9/00;A61K9/14;A61K38/00;A61K38/18;A61K47/48;C07K14/505;C07K14/53;C07K14/54;C07K14/55;C07K14/56;C07K14/565;C07K17/06;C07K17/10;C08B31/00;C08B31/08;C08B31/12;C08B33/04;C08B35/04;C12N15/12;(IPC1-7):C07K14/505 |
主分类号 |
A61K8/73 |
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