发明名称 |
PROCESS FOR THE DETERMINATION OF PEPTIDES CORRESPONDING TO IMMUNOLOGICALLY IMPORTANT EPITOPES AND THEIR USE IN A PROCESS FOR DETERMINATION OF ANTIBODIES OR BIOTINYLATED PEPTIDES CORRESPONDING TO IMMUNOLOGICALLY IMPORTANT EPITOPES, A PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM |
摘要 |
This invention is directed toward a peptide corresponding to an immunologically important viral epitope. Specifically, the peptide corresponds to an immunodominant epitope identified in the envelope region of the human immunodeficiency virus type 1 (HIV-1). This peptide has the following amino acid sequence: NH2-Asn-Asn-Thr-Arg-Arg-Gly-Ile-His-Met-Gly-Trp-Gly-Arg-Thr-Phe-Tyr-Ala-Thr-Gly-Glu-Ile-Ile-Gly-CO2H (SEQ ID NO:17). The invention also relates to the use of this peptide, particularly when biotinylated in the form of complexes of streptavidin-biotinylated peptides or of avidin-biotinylated peptides, for the in vitro determination of HIV-1-specific antibodies.
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申请公布号 |
US6709828(B1) |
申请公布日期 |
2004.03.23 |
申请号 |
US20000680497 |
申请日期 |
2000.10.06 |
申请人 |
N.V. INNOGENETICS S.A. |
发明人 |
DE LEYS ROBERT |
分类号 |
C07K1/13;C07K14/16;C07K14/18;G01N33/531;G01N33/569;G01N33/68;(IPC1-7):G01N33/53 |
主分类号 |
C07K1/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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