STABILIZED PROTEINS WITH ENGINEERED DISULFIDE BONDS
摘要
The present invention relates to methods of introducing one or more cysteine residues into a polypeptide which permit the stabilization of the polypeptide by formation of at least one bond, preferably a disulfide bond, between different domains of the polypeptide (Figure 1).
申请公布号
WO02103024(A3)
申请公布日期
2004.03.18
申请号
WO2002US19017
申请日期
2002.06.14
申请人
THE SCRIPPS RESEARCH INSTITUTE;GRIFFIN, JOHN, H.;GALE, ANDREW, J.;GETZOFF, ELIZABETH, D.;PELLEQUER, JEAN-LUC
