IMMUNOTHERAPY USING MODULATORS OF NOTCH SIGNALLING

摘要

There is provided a use of a modulator of Notch signalling for the preparation of a medicament for treatment of Graft Versus Host Disease (GVHD) and diseases and conditions caused by or associated with transplants such as organ, tissue and/or cell transplants (e.g. bone marrow transplants), wherein the modulator is used to reduce the reactivity of cells of the immune system.