Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
申请公布号
CA2824167(A1)
申请公布日期
2004.03.18
申请号
CA20032824167
申请日期
2003.09.05
申请人
AMGEN INC.;MEDAREX, INC.
发明人
VARNUM, BRIAN;VEZINA, CHRIS;WHITTE, ALISON;QIAN, XUEMING;MARTIN, FRANCIS HALL;HUANG, HAICHUN;ELLIOTT, GARY