发明名称 |
ANTIBODY AGAINST SECRETED N-TERMINAL PEPTIDE OF GPC3 PRESENT IN BLOOD |
摘要 |
Disclosed is an antibody against a secreted form of GPC3 capable of detecting a secreted form of glypican 3 (GPC3) in a test sample. It is possible to determine whether a subject suffers from cancer, in particular hepatoma. Also disclosed is an antibody against GPC as well as a cell disrupting agent and an anti-cancer agent comprising the same, which can disrupt cells, in particular cancer cells. Specifically, the invention relates to an isolated antibody that binds to an N-terminal peptide of glypican-3 (GPC3).
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申请公布号 |
CA2801911(A1) |
申请公布日期 |
2004.03.18 |
申请号 |
CA20032801911 |
申请日期 |
2003.09.04 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
ABURATANI, HIROYUKI;MIDORIKAWA, YUTAKA;NAKANO, KIYOTAKA;OHIZUMI, IWAO;ITO, YUKIO;TOKITA, SUSUMU |
分类号 |
C07K16/18;C07K16/28;C12N15/06;C12N15/08;C12P21/08;G01N33/543;G01N33/574;G01N33/577 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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