| 摘要 |
To establish pregnancy, it is important that an embryo well communicates wit h the parent body and thus is allowed to implant in the uterine wall. Clarification and regulation of a factor mediating the embryo-parent body communication, if possible, enable the development of means of treating and preventing disorders such as infertility. On the other hand, it also becomes possible to safely avoid pregnancy thereby. A protein factor having been kno wn as a 10 KDa protein (IP-10) usually induced by interferon .gamma. is identified as a factor which participates in the immune process, activation of embryo migration, promotion of embryo implantation in the uterine wall, exertion of the chemotaxis activity, etc. during the period of the implantation of the embryo in the parenteral body and thus controls the implantation of the embryo in the uterine wall. Using this factor, it is possible to develop and provide a remedy for infertility, a pregnant efficiency enhancer, an agent for inducing an embryo into the uterine during the implantation period, an agent controlling the fetal-parenteral body interaction and so on.
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