发明名称 |
USE OF CHLOROQUINE, HYDROXYCHLOROQUINE, AND 4-AMINO-QUINOLINIC ACID DERIVATIVE FOR OBTAINING ANTI-RETROVIRUS THERAPEUTIC AGENT HAVING ACTIVITY AGAINST HIV STRAIN |
摘要 |
PROBLEM TO BE SOLVED: To provide a method for use, relating to pharmacological and therapeutical fields and in particular of chloroquine, hydroxychloroquine, and 4-amino-quinolinic acid derivatives for obtaining an anti-retroviruse therapeutic agent having an activity against HIV sensitive strains and also having an activity against HIV strains which have resistance against current anti-HIV therapies. SOLUTION: At least one 4-amino-quinolinic acid derivative is used for obtaining an anti-retrovirus therapeutic agent, in particular a therapeutic agent for treating HIV infectious diseases caused by retrovirus strains which have sensitivity and/or resistance against known therapies. The 4-amino-quinolinic acid derivatives are chloroquine and/or hydroxychloroquine and the agent can be orally administered once or few times a day. COPYRIGHT: (C)2004,JPO
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申请公布号 |
JP2004083576(A) |
申请公布日期 |
2004.03.18 |
申请号 |
JP20030180625 |
申请日期 |
2003.06.25 |
申请人 |
VALPHARMA SA |
发明人 |
VALDUCCI ROBERTO;ALIGHIERI TIZIANO;AVANESSIAN SEROZH |
分类号 |
C07D215/46;A61K31/4706;A61P31/14;A61P31/18;A61P43/00;(IPC1-7):A61K31/470 |
主分类号 |
C07D215/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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