| 发明名称 |
Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine-mediated toxicity |
| 摘要 |
The present invention relates to compositions and methods for inhibiting the release and/or biological activity of migration inhibitory factor (MIF). In particular, the invention relates to the uses of such compositions and methods for the treatment of various conditions #involving cytokine-mediated toxicity, which include, but are not limited to shock, inflammation, graft versus host disease, and/or autoimmune diseases.
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| 申请公布号 |
US2004053843(A1) |
申请公布日期 |
2004.03.18 |
| 申请号 |
US20030462751 |
申请日期 |
2003.06.17 |
| 申请人 |
BUCALA RICHARD J.;MITCHELL ROBERT A.;BERNHAGEN JURGEN;CALANDRA THIERRY F.;CERAMI ANTHONY |
发明人 |
BUCALA RICHARD J.;MITCHELL ROBERT A.;BERNHAGEN JURGEN;CALANDRA THIERRY F.;CERAMI ANTHONY |
| 分类号 |
A61K39/395;A61K48/00;A61P43/00;C07K14/52;C07K14/575;C07K14/72;C07K16/24;C07K16/26;C12N15/113;C12N15/85;(IPC1-7):A61K39/395;A61K31/00;A61K38/17 |
主分类号 |
A61K39/395 |
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