发明名称 |
Nmda receptor channel blocker with neuroprotective activity |
摘要 |
Neuroprotectant agents are provided which do not contain peptides and are protected from the degradation that limits the use of peptide-based drugs in systemic circulation. With great selectivity for NMDA receptors, the agents exert an open channel block on NMDA receptors, and protect neuronal cells containing such receptors from excitotoxic cell death.
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申请公布号 |
US2004054013(A1) |
申请公布日期 |
2004.03.18 |
申请号 |
US20030381956 |
申请日期 |
2003.09.25 |
申请人 |
TAI KWOK-KEUNG;BLONDELLE SYLVIE E.;HOUGHTEN RICHARD A.;MONTAL MAURICIO |
发明人 |
TAI KWOK-KEUNG;BLONDELLE SYLVIE E.;HOUGHTEN RICHARD A.;MONTAL MAURICIO |
分类号 |
A61K31/00;A61K31/137;C07B61/00;C07C211/27;C07C211/30;C07C215/54;(IPC1-7):A61K31/137 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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