| 摘要 |
The invention relates to the use of known pharmaceutical substances chloropromazine, ethacrine, quinacrine, lovastatine, doxorubicine and D-penicillamine for the diagnosis of human and animal neurodegenerative diseases such prion diseases as TSE diseases suc has BSE, CJD, vCJD, scrapie and other neurodegenerative diseases based on the formation of neurotoxic amyloid plaques. Body fluids such as whole blood, plasma, serum, liquor, urine, milk, lymph, lymph plasma and saliva, i.e. body fluids containing proteins, are used as test media. Previously, said substances were used therapeutically as psychopharmaceuticals, cycostatics, lipid reducres, antirheumatics and antiparasite agents. The invention also relates to a method for the diagnosis of human and animal neurodegenerative diseases, wherein said pharmaceutical substances are used. |
