PHARMACEUTICAL DOSAGE FORM COMPRISING A SULFITE COMPOUND
摘要
The present invention provides a pharmaceutical dosage form comprising a fill material sealed in a gelatin capsule; the fill material comprises (a) a selective COX-2 inhibitory drug of low water solubility, and (b) a sulfite compound in an amount sufficient to inhibit cross-linking of gelatin in said gelatin capsule upon storage of the dosage form in a closed container maintained at 40 DEG C and 75% relative humidity for a period of 6 months.
申请公布号
WO2004022032(A2)
申请公布日期
2004.03.18
申请号
WO2003US24044
申请日期
2003.07.31
申请人
PHARMACIA CORPORATION;GAO, PING;BAUER, JULIANE, M.;EWING, GARY;SPERRY, DAVID
发明人
GAO, PING;BAUER, JULIANE, M.;EWING, GARY;SPERRY, DAVID