| 摘要 |
<p>Acrylamide derivatives with a cycloalkylidenacetamide-like structure having at least 3 cyclic groups, for example, 2-(1-benzoylpiperidin-4-ylidene)-N-{1-[(6-fluoronaphthalen-2-yl)methyl]pyrrolidin-3-yl}acetamide or salts thereof. Because of having an excellent CCR3 antagonism, these compounds are efficacious in treating diseases in which CCR3 participates, for example, asthma.</p> |
| 申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD.;TORAY INDUSTRIES, INC.;MORIHIRA, KOICHIRO;KUBOTA, HIROKAZU;SATO, IPPEI;YOKOYAMA, KAZUHIRO;MOROKATA, TATSUAKI;YOKOTA, MASAKI;IMAOKA, TAKAYUKI;KANEKO, MASAYUKI;FUNAHASHI, MIYUKI;KANEEDA, MASANOBU |
发明人 |
MORIHIRA, KOICHIRO;KUBOTA, HIROKAZU;SATO, IPPEI;YOKOYAMA, KAZUHIRO;MOROKATA, TATSUAKI;YOKOTA, MASAKI;IMAOKA, TAKAYUKI;KANEKO, MASAYUKI;FUNAHASHI, MIYUKI;KANEEDA, MASANOBU |
