| 发明名称 |
ORTHOPOXVIRUS VECTORS, GENES AND PRODUCTS THEREOF |
| 摘要 |
<p>An orthopoxvirus vector, such as vaccinia, is described in which the A52R protein from vaccinia, or a closely related protein from any orthopoxvirus i s not expressed or is expressed but is non-functional. Also described is the u se of a vaccinia virus A52R protein or a closely related protein from any orthopoxvirus, or a functional peptide, peptidometic, fragment or derivative thereof, or a DNA vector expressing any of the above in the modulation and/o r inhibition of IL1R/TLR superfamily signalling.</p> |
| 申请公布号 |
CA2497750(A1) |
申请公布日期 |
2004.03.18 |
| 申请号 |
CA20032497750 |
申请日期 |
2003.09.05 |
| 申请人 |
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVID ED |
发明人 |
SMITH, GEOFFREY LILLEY;HAGA, ISMAR ROCHA;MALONEY, GERALDINE;HARTE, MARY THERESA;BOWIE, ANDREW GRAHAM;O'NEILL, LUKE ANTHONY JOHN |
| 分类号 |
A61K35/76;A61K38/00;A61K38/11;A61K38/16;A61K39/00;A61K39/12;A61K39/285;C07K14/07;C12N7/00;C12N7/04;C12N15/86;C12N15/863;(IPC1-7):C12N15/86 |
主分类号 |
A61K35/76 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
