发明名称 |
USE OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR)-GAMMA LIGANDS AS A TREATMENT FOR PITUITARY TUMORS AND ASSOCIATED CONDITIONS, SUCH AS CUSHING'S SYNDROME |
摘要 |
Disclosed is a method for treating a pituitary tumor in a mammal, employing the administration of a peroxisome proliferator activated receptor gamma ligand (also known as "peroxisome proliferating-activator receptor gamma" or "PPAR-Upsilon"). In some embodiments, the peroxisome proliferator activated receptor gamma ligand is a thiazolidinedione compound. Also disclosed are methods for preventing the formation of a pituitary tumor in a mammal and for preventing the recurrence of a pituitary tumor in a mammal. Further disclosed is a method for treating a mammal exhibiting one or more symptoms of Cushing's syndrome.
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申请公布号 |
WO03101403(A8) |
申请公布日期 |
2004.03.18 |
申请号 |
WO2003US19060 |
申请日期 |
2003.06.04 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
HEANEY, ANTHONY, P.;MELMED, SHLOMO |
分类号 |
A61K31/426;A61K31/4439;(IPC1-7):A61K/ |
主分类号 |
A61K31/426 |
代理机构 |
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