| 发明名称 |
SUSTAINED RELEASE FORMULATION |
| 摘要 |
<p>A composition comprises a protein, a polyol, and a metal. The protein is stabilized by the polyol and the metal, and is protected from denaturing when in contact with an organic solvent. The polyol may be a hydrocarbon containing two or more hydroxyl groups (-OH) bonded to carbon. The metal may be divalent.</p> |
| 申请公布号 |
EP1397155(A1) |
申请公布日期 |
2004.03.17 |
| 申请号 |
EP20020749622 |
申请日期 |
2002.06.21 |
| 申请人 |
GENENTECH, INC. |
发明人 |
OKUMU, FRANKLIN;CLELAND, JEFFREY, L. |
| 分类号 |
A61K9/10;A61K33/30;A61K9/00;A61K38/00;A61K38/18;A61K38/27;A61K38/28;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/26;A61K47/34;A61K47/36;A61P5/06;A61P5/50;(IPC1-7):A61K38/27 |
主分类号 |
A61K9/10 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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