发明名称 |
PROCESS FOR THE PREPARATION OF RIBAVIRIN. |
摘要 |
<p>A process for the preparation of ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid. Said process comprises:a) the reaction of a triazole of the formula (I) (see enclosed paper copy)with a protected ribofuranose of the formula (II) (see enclosed paper copy)b) the removal of the Pg groups and, optionally, the conversion into a carboxyamide group of the R2 group of the compound obtained of the formula (III) (see enclosed paper copy).</p> |
申请公布号 |
MXPA03010251(A) |
申请公布日期 |
2004.03.16 |
申请号 |
MX2003PA10251 |
申请日期 |
2002.07.29 |
申请人 |
CLARIANT LIFE SCIENCE MOLECULES (ITALIA) S.P.A. |
发明人 |
BANFI ALDO |
分类号 |
A61K31/7056;A61P31/12;C07H1/00;C07H19/056;(IPC1-7):A61K31/705 |
主分类号 |
A61K31/7056 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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